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The principal cytochrome P450 isoenzyme concerned seems to get CYP2E1, with CYP1A2 and CYP3A4 as more pathways. About eighty five% of an oral dose seems inside the urine in just 24 several hours of administration, most given that the glucuronide conjugate, with modest quantities of other conjugates and unchanged drug [see OVERDOSAGE] for toxicity d